MamoScope

Three-Dimensional Insight for Intraoperative Decision Support.

A patented deep-technology platform developed from academic research in 3D imaging and reconstruction.

Flagship Deep-Technology Platform

Non-Destructive 3D Imaging of Excised Breast Tissue.

MamoScope is an X-ray-based imaging and decision-support platform designed to create volumetric and three-axis sectional images of excised breast tissue during surgery, providing additional information for surgical margin assessment.

How It Works Research Inquiry
Platform Role

Complementary to Pathology

MamoScope is positioned as a non-destructive imaging and AI-driven decision-support technology that complements established pathological examination rather than replacing it.

ACQUISITION360° X-ray
OUTPUT3-Axis + 3D
SAMPLENon-Destructive
ANALYSISAI-Driven
Clinical Motivation

More Information While the Operation Is Still in Progress

Final pathology may require an extended laboratory workflow. During breast-conserving surgery, clinicians need additional information about whether the excised tissue margins appear clear before the operation is completed.

MamoScope was developed to image the intact excised specimen in three dimensions and support the surgical team with a digital, reviewable dataset during the intraoperative period.

Designed Contribution

Non-Destructive ExaminationThe tissue can be imaged without creating physical sections for the scan.
Three-Dimensional ContextVolumetric data and orthogonal sections allow the specimen to be reviewed from multiple planes.
Digital Decision SupportReconstruction and AI-driven analysis can provide additional structured information to clinicians.
Archivable DatasetThe resulting images can be reviewed, compared and retained as digital data.
Imaging Workflow

From Excised Tissue to Three-Dimensional Review

The platform integrates acquisition, reconstruction and analysis within a single imaging workflow.

STEP 01

Specimen Placement

The surgically excised tissue is positioned for non-destructive imaging without sectioning it for the scan.

STEP 02

360° Acquisition

X-ray projection images are collected around the specimen through a full rotational scan.

STEP 03

3D Reconstruction

Projection data are reconstructed into axial, sagittal and coronal sections and a volumetric dataset.

STEP 04

Clinical Review Support

The reconstructed dataset and AI-driven outputs provide additional information for margin assessment.

The supplied project materials describe an imaging objective of approximately 10 minutes; actual workflow time depends on specimen and scan configuration.

System Capabilities

A Specialized 3D Imaging Architecture

MamoScope applies OpTomo's broader imaging-center competencies to the demanding requirements of breast-tissue imaging.

Up to 3200 Projections

Dense projection acquisition for detailed reconstruction workflows.

Three Orthogonal Axes

Axial, sagittal and coronal sectional review of the reconstructed specimen.

Volumetric Visualization

Three-dimensional reconstruction for whole-specimen spatial interpretation.

Multi-Format Digital Outputs

Section images, volumetric files, videos and analysis outputs for review and archiving.

Academic Origin

Developed from Long-Term Research in 3D Imaging

MamoScope was developed by Assoc. Prof. Dr. Adem Polat, whose research includes 3D image reconstruction for digital breast tomosynthesis and CT, microscale biological imaging and optical tomography.

The platform builds on internationally conducted academic work at Harvard Medical School, Harvard-MIT HST, University of Lisbon, İTÜ and ÇOMÜ; TÜBİTAK and TÜSEB-supported projects, scientific publications and an intellectual-property portfolio in three-dimensional imaging systems.

Intellectual Property

  • Turkish Patent: TR 2022 014148 B
  • International filing/report: PCT/TR2023/050948
  • US publication: US 2026/0092881
  • MamoScope trademark: 2024 164715